منابع مشابه
Jean Leray (1906–1998), Volume 47, Number 3
Jean Leray was first and foremost an analyst. His involvement with algebraic topology was initially incidental and became later, at first for nonmathematical reasons, a topic of major interest for him for about ten years. His papers are written with his own notation and conventions, which, for the most part, have not been adopted and are consequently little read today. But it is there that shea...
متن کاملMarguerite Bottard (1822-1906), nurse under Jean-Martin Charcot, portrayed by G. Gilles de la Tourette.
Hospitals in Paris underwent considerable change at the end of the 19th century. As they moved from providing accommodation to care, their mission shifted from helping to healing. The glorification of scientific progress, as opposed to religious obscurantism, affected all of French 'Republican' society, in particular a significant part of the medical profession, led by figures such as D.M. Bour...
متن کاملDmd053405 1906..1913
Carbinol [4,49-(hydroxymethylene)dibenzonitrile] is the main phase 1 metabolite of letrozole, a nonsteroidal aromatase inhibitor used for endocrine therapy in postmenopausal breast cancer. We elucidated the contribution of UDP-glucuronosyltransferase (UGT) isoforms on the glucuronidation of carbinol. Identification of UGT isoforms was performed using a panel of recombinant human UGT enzymes. Ki...
متن کاملPierre Curie, 1859–1906
The year 2006 marked 100 years since the death of Pierre Curie. It is therefore appropriate that we remember his life and his work, which was cut short by his untimely death from an accident on the Pont Neuf, Paris, on April 19, 1906. He had already accomplished much during his life, both before the discovery of radium with Marie Curie, in work co-authored with his brother Jacques on piezoelect...
متن کاملJean - Paul Fermand and Jean - Claude Brouet
In the majority o f chronic lymphocytic leukemias (CLL), proliferative B lymphocytes are thought to be frozen in vivo at a given maturat ion stage (1). Recently, several studies have emphasized that CLL cells could be driven to different iate into plasma cells in vitro (with or without proliferation) upon t r iggering by mitogens (2, 3, 4) or T cel l -der ived factors (5, 6). Th u s far, howeve...
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ژورنال
عنوان ژورنال: Nature
سال: 1999
ISSN: 0028-0836,1476-4687
DOI: 10.1038/17237